A new way to open biology books: listen to mitotic rap!
A new way to open biology books: listen to mitotic rap!
Have a little rhythm on the weekend.

give mitosis a little rhythm! Let's listen to a biological rap:

Video from: sciencemusicvideos

the following are the lyrics (and the rough translation _ ("∠") _):

Interphase is cell division\'s longest part,

the interphase is the longest part of cell division

nuclear membrane\'s intact as it starts,

it begins with a complete nuclear membrane

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cell growth. Cytoplasmic flow

chromosomes get duplicated, DNA gets replicated

chromosomes and DNA can be copied

>

chromatin is scattered, so it is not true to see

But note the nucleolus, the ribosome factory

but look at nucleoli, this ribosome factory

Outside the nucleus are two centrosomes,

outside are two centrosome

They later make a spindle which will pull apart the chromosomes.

cell growth. Cytoplasmic flow

chromosomes get duplicated, DNA gets replicated

chromosomes and DNA can be copied

chromatin is scattered, so it is not true to see

But note the nucleolus, the ribosome factory

but look at nucleoli, this ribosome factory

Outside the nucleus are two centrosomes,

outside are two centrosome

they will later form spindle filaments. Pull apart the chromosomes

then comes the Prophase, shrinking into chromosomes

Each is made of two sister chromatids, (looks) like an\ "X\"

each is a pair of sister monomers, which looks like X

Each sister is a clone, the closest of kin,

each sister is cloned, and the nearest relative

centromere is attached to them. Just like Siamese twins

The nucleolus disappears it melts away,

nucleolus disappears

as the cell takes a ribosome production holiday,

cells release ribosome production leave

centrosome separate, forming spindle

in order to separate chromatids, the cells elongate

mitosis. Chromosome movement

Inter-, pro-, meta-, ana-, telophase, divide

interphase, anterior, middle, posterior and terminal stages, cell division

Eukaryotes go from one cell to two,

eukaryote

Mitosis, how cells renew

mitosis. The cell thus updates

The nuclear membrane disintegrates,

nuclear membrane disintegration

The centrosomes migrate to the cell\'s opposing sides,

And between them the fibers of the spindle wend and wind,

the spindle extends between them

spindle consists of microtubules.

to chromosomes at kinetochores, a protein patch

it connects chromosomes through centromere,

that serves like a hanDle that the fibers can grasp,

centromere is like a handle that these fibers can grasp

When they pull apart the chromosomes, splitting them in half,

pull chromosomes. Divide them into two halves

The spindle moves the chromosomes with nudges so fine,

spindle filaments finely move chromosomes

Into linear formation on the 50 yard line

line up at 50 yard line (note: 50 yard line is the middle of the American football field)

A location equatorial defining metaphase,

position at the equator This defines

where the chromosomes are lined up on that middle place

chromosomes arranging in the middle

CHORUS

The spindle fibers pull on the kinetochores,

spindle pulling centromere

centromere is like a handle that these fibers can grasp

When they pull apart the chromosomes, splitting them in half,

pull chromosomes. Divide them into two halves

The spindle moves the chromosomes with nudges so fine,

spindle filaments finely move chromosomes

Into linear formation on the 50 yard line

line up at 50 yard line (note: 50 yard line is the middle of the American football field)

A location equatorial defining metaphase,

position at the equator This defines

where the chromosomes are lined up on that middle place

centromere is like a handle that these fibers can grasp

When they pull apart the chromosomes, splitting them in half,

pull chromosomes. Divide them into two halves

The spindle moves the chromosomes with nudges so fine,

spindle filaments finely move chromosomes

Into linear formation on the 50 yard line

line up at 50 yard line (note: 50 yard line is the middle of the American football field)

A location equatorial defining metaphase,

position at the equator This defines

chromosomes arranging in the middle

CHORUS

The spindle fibers pull on the kinetochores,

A cellular molecular mitotic tug of war,

The centromere snaps, sisters get separated,

centromere disconnection. Sister segregation

Now these chromatids are chromosomes, they\'ve been upgraded

This snapping separation defines anaphase

The\ "A\" for\ "apartness\", for moving different ways,

An is separate A. Go their separate ways

Kinetochore spindle fibers separate the sisters

the spindle thread pulls the centromere to separate the sisters

watch them wave goodbye. Shout "I will miss you"

And the other spindle fibers push and grapple like felons

Makes the cell elliptical like a watermelon,

cells become oval like watermelons

form membranes around terminal chromosomes

The nucleolus comes back

In animal cells there\'s a ring of microfilaments

there is a circle of microfilaments

that form at the equator and they cinch themselves in

forms a contraction ring at the equator and tightens itself

tight, then tight until the cell divides into two halves

Yeah in animals, that\' s cytokinesis

This is cytokinesis

By building a new cell wall from the inside

As the Golgi sends vesicles with cellulosic goo,

Golgi sends vesicles filled with "cellulose glue"

Which makes a plate, then a wal.L, divides the cell in two

it forms a cell board and divides the cell into two

And instead of one mother cell we now have daughters two

identical twins, both "new" and "old",

From your single celled beginning this is how you grew

start with one cell. This is how you grow

And for single celled eukaryotes it\'s reproductive too!

and for single-celled eukaryotes, this is also reproduction!